An Innovative Polymeric Platform for Controlled and Localized Drug Delivery

Precision medicine aims to optimize pharmacological treatments by considering patients’ genetic, phenotypic, and environmental factors, enabling dosages personalized the individual. To address challenges associated with oral injectable administration approaches, implantable drug delivery systems have been developed. These overcome issues like patient adherence, bioavailability, first-pass metabolism. Utilizing new combinations of biodegradable polymers, proposed solution, a Polymeric Controlled Release System (PCRS), allows minimally invasive placement controlled over several weeks. This study’s objective was show that PCRS exhibits linear biphasic release profile, which would indicate potential as an effective treatment vehicle for cervical malignancies. An injection mold technique developed batch manufacturing devices, in vitro experiments demonstrated device’s geometry surface area could be varied achieve various profiles. results motivate additional development treat cancer, well other malignancies, such lung, testicular, ovarian cancers.